Veterinary analyzer AriaDNA

bacteriabenchtopreal-time

About Polymerase chain reaction (PCR) remains a cornerstone technique in clinical and research laboratories for qualitative and quantitative nucleic acid analysis, pathogen detection, genotyping and genetic disease diagnostics. The microchip-based real-time PCR analyzer AriaDNA is designed for rapid, low-volume molecular testing in diagnostic and laboratory settings.

Key features

• Rapid PCR cycle – complete 45-cycle analysis in approximately 20 minutes thanks to high thermocycling rates (heating 12 °C/s, cooling 10 °C/s)
• Minimal sample and reagent volume – 0.5–1.8 μl sample with 0.5–1.8 μl of 2× PCR master mix per microreactor
• High analytical sensitivity – detection limits of 1–5 DNA/RNA copies per microreactor
• Preloaded microchips available – microchips with immobilized, ready-to-use PCR reagents to simplify workflow
• Multiplex detection – qualitative and quantitative analysis across 20–48 microreactors via two optical channels (FAM, SYBR Green / ROX, Cy5)
• Contamination control – sealed microchip format isolates reactions from environment
• Real-time monitoring – live display of temperature, cycle progress, estimated time to completion, amplification curves and result calls
• Intuitive graphical interface – operator-friendly software for routine lab use
• Automatic report generation
• Regulatory support – CFR 21 Part 11 compliant
• Data export – results exportable in standard industry formats

Application areas

• Clinical diagnostics laboratories (human and veterinary)
• Infectious disease and public-health testing centers
• Food safety and quality control laboratories
• Reference and research laboratories for genotyping and mutation analysis

Microchips and reagents

• Microchips support user-loaded PCR reagents or preloaded lyophilized formulations depending on workflow needs
• Lyophilized reagent chips designed for infectious disease detection, SNP and hereditary-disease panels; stable at ambient temperature for up to 6 months
• Example assays: STI panels (Trichomonas, Candida, Mycoplasma, Chlamydia, Neisseria, HSV I/II), SNP testing (F2, F5, MTHFR, CYP2C9, VKORC1), livestock/poultry pathogen detection, pathogen screening in raw and processed foods

Technical specifications

• Thermal cycling rate: heating 12 °C/s; cooling 10 °C/s
• Limit of detection: 1–5 DNA copies per microreactor
• Sample volume per analysis: 0.5–1.8 μl
• Total PCR time (45 cycles): ~20 minutes
• Microreactors per chip: 20, 24, 30, 48
• Reagent volume (2× PCR mix): 0.5–1.8 μl
• Microchips with immobilized reagents: available on request
• Detection channels / dyes: Channel 1 – FAM, SYBR-Green I; Channel 2 – ROX, Cy5
• External control: USB 2.0
• Software for PCR analysis, instrument setup and database management: included
• Power: 90–240 VAC, 50/60 Hz; consumption 100 W
• Dimensions: 250 × 300 × 190 mm
• Weight: 5 kg